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IV V V
ค ำย่อ PDR: proliferative diabetic retinopathy
PI-3: phosphatidylinositol-3
ACEIs: angiotensin converting enzyme inhibitors PPAR: peroxisome proliferator-activated receptor gamma
ADA: American Diabetes Association PPG: postprandial glucose
ADP: adenosine diphosphate RAGEs: receptors for advanced glycation end products
AGEs: advanced glycation end products RI: regular insulin
AMPK: adenosine monophosphate-activated protein kinase SGLT: sodium-glucose cotransporter
ARBs: angiotensin II receptor blockers STZ: streptozotocin
ASCVD: atherosclerotic cardiovascular disease T1DM: Type 1 diabetes mellitus
ATP: adenosine triphosphate T2DM: Type 2 diabetes mellitus
BMI: body mass index Tyr: tyrosine
CABG: coronary artery bypass graft VA: visual acuity
CVA: cerebrovascular accident VLDL-C: Very low-density lipoprotein cholesterol
Cmax: maximum (or peak) serum concentration
CYP: cytochrome P450
DKA: diabetic ketoacidosis
DPP-4: dipeptidyl peptidase-4
eGFR: estimated glomerular filtration rate
FPG: fasting plasma glucose
GDM: gestation diabetes mellitus
GLP-1: glucagon-like peptide-1
GLUT: glucose transporters
HbA1C: glycosylated hemoglobin
HDL-C: high-density lipoprotein cholesterol
HHS: hyperosmolar hyperglycemic syndrome
IC50: the half maximal inhibitory concentration
IFG: impaired fasting glucose
IGT: impaired glucose tolerance
IRS: insulin receptor substrate
LDL-C: low-density lipoprotein cholesterol
MALA: metformin-associated lactic acidosis
MAP: Mitogen-activated protein
NPDR: non-proliferative diabetic retinopathy
NPH: neutral protamine hagedorn
OATP: organic-anion transporting polypeptides
OGTT: oral glucose tolerance test